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Keppeke Gerson, Dierley

Académico

Posiciones

Académico, Departamento de Ciencias Biomédicas 2003 -

Enfoque geográfico

Brazil País

publicaciones seleccionadas

artículo editorial
- Precision medicine for Autoimmunity: From CAAR-T Cells to AI-Driven CRISPR-based therapies, challenges and perspectives. GenoMed Connect. 2025
- The IMPDH cytoophidium couples metabolism and fetal development in mice. Cellular and Molecular Life Sciences. 2024
- Detection of Autoantibodies Against the Acetylcholine Receptor, Evaluation of Commercially Available Methodologies: Fixed Cell-Based Assay, Radioimmunoprecipitation Assay and Enzyme-Linked Immunosorbent Assay. Journal of Neuromuscular Diseases. 2024
- "Untargeting" autoantibodies using genome editing, a proof-of-concept study.. Clinical immunology (Orlando, Fla.). 2023
- Detection of autoantibodies against the acetylcholine receptor, evaluation of commercially available methodologies: fixed Cell-Based Assay, Radioimmunoprecipitation Assay and Enzyme-Linked Immunosorbent Assay. MedRxiv,. 2023
- Effect on cell survival and cytoophidium assembly of the adRP-10-related IMPDH1 missense mutation Asp226Asn. Frontiers in Cell and Developmental Biology. 2023
- Evaluation of commercially available chemical reagents and electroporation for insertion of nucleic acids into hard-to-transfect cells. Genetics and Molecular Research. 2023
- A cell-based assay for detection of anti-fibrillarin autoantibodies with performance equivalent to immunoprecipitation. Frontiers in Immunology. 2022
- ''UNTARGETING'' AUTOANTIBODIES USING GENOME EDITING, A PROOF-OF-CONCEPT STUDY. bioRxiv. 2022
- A CELL-BASED ASSAY FOR DETECTION OF ANTI-FIBRILLARIN AUTOANTIBODIES IN SYSTEMIC SCLEROSIS. MedRxiv,. 2022
- Molecular crowding facilitates bundling of IMPDH polymers and cytoophidium formation. Cellular and Molecular Life Sciences. 2022
- Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study (vol 12, 709861, 2021). Frontiers in Immunology. 2022
- Serum Myostatin and Follistatin Levels in Patients With Dermatomyositis and Polymyositis. Journal of Clinical Rheumatology. 2022
- CTPS forms the cytoophidium in zebrafish. Experimental Cell Research. 2021
- IMPDH forms the cytoophidium in zebrafish. Developmental Biology. 2021
- Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study. Frontiers in Immunology. 2021
- IMP dehydrogenase rod/ring structures in acral melanomas. Pigment Cell & Melanoma Research: The Official Journal of the International Federation of Pigment Cell Societies and the Society for Melanoma Research. 2020
- IMPDH-Based Cytoophidium Structures as Potential Theranostics in Cancer. Molecular Therapy. 2020
- Ribavirin induces widespread accumulation of IMP dehydrogenase into rods/rings structures in multiple major mouse organs. Antiviral Research. 2019
- IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Cell Division. 2018
- Interfilament interaction between IMPDH and CTPS cytoophidia. The FEBS Journal. 2018
- Psychological characteristics of caregivers of pediatric patients with chronic rheumatic disease in relation to treatment adherence. Pediatric Rheumatology. 2018
- CTP synthase forms the cytoophidium in human hepatocellular carcinoma. Experimental Cell Research. 2017
- Anti-rods/rings autoantibody generation in hepatitis C patients during interferon-alpha/ribavirin therapy. World Journal of Gastroenterology. 2016
- Differential capacity of therapeutic drugs to induce Rods/Rings structures in vitro and in vivo and generation of anti-Rods/Rings autoantibodies. Clinical Immunology. 2016
- Anti-rods/rings: a human model of drug-induced autoantibody generation. Frontiers in Immunology. 2015
- Assembly of IMPDH2-Based, CTPS-Based, and Mixed Rod/Ring Structures Is Dependent on Cell Type and Conditions of Induction. Journal of Genetics and Genomics. 2015
- Microinjection of specific anti-IMPDH2 antibodies induces disassembly of cytoplasmic rods/rings that are primarily stationary and stable structures. Cell & Bioscience. 2015
- Mycophenolic Acid and Ribavirin Induces Cytoplasmic Autoimmunogenic Rods and Rings Structures in Vivo. Arthritis & Rheumatology. 2014
- Temporal evolution of human autoantibody response to cytoplasmic rods and rings structure during anti-HCV therapy with ribavirin and interferon-alpha. Immunologic Research. 2014
- Longitudinal Study of a Human Drug-Induced Model of Autoantibody to Cytoplasmic Rods/Rings following HCV Therapy with Ribavirin and Interferon-alpha. PLOS ONE. 2012
capítulo
- Future Direction of Laboratory Testing for Autoimmune Diseases. Manual of Molecular and Clinical Laboratory Immunology. 2024

correo electrónico principal

gerson.keppeke@ucn.cl

correos electrónicos adicionales

gerson.keppeke@gmail.com

página web

ORCID

https://orcid.org/0000-0003-0660-2857

OpenAlex

https://openalex.org/authors/a5024781972

Publicaciones en VIVO

Mapa de la ciencia

Información de Contacto

gerson.keppeke@ucn.cl

gerson.keppeke@gmail.com

Sitios web