publicaciones seleccionadas
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artículo editorial
- DNA damage in a Chilean population exposed to pesticides and its association with PON1 (Q192R and L55M) susceptibility biomarker. Environmental and Molecular Mutagenesis. 2022
- Differential Distribution and Activity Profile of Acylpeptide Hydrolase in the Rat Seminiferous Epithelium. Biomedicines. 2022
- A positive relationship between exposure to heavy metals and development of chronic diseases: A case study from chile. International Journal of Environmental Research and Public Health. 2021
- Levels of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in human breast milk in Chile: A pilot study. International Journal of Environmental Research and Public Health. 2021
- Pesticide exposure in Chile and population health: urgency for decision making,Exposición a plaguicidas en Chile y salud poblacional: urgencia para la toma de decisiones. GACETA SANITARIA. 2021
- Association between cholinesterase's inhibition and cognitive impairment: A basis for prevention policies of environmental pollution by organophosphate and carbamate pesticides in Chile. Environmental Research. 2020
- Reduced neurobehavioral functioning in agricultural workers and rural inhabitants exposed to pesticides in northern Chile and its association with blood biomarkers inhibition. Environmental Health: A Global Access Science Source. 2020
- Biomonitoring of blood cholinesterases and acylpeptide hydrolase activities in rural inhabitants exposed to pesticides in the Coquimbo Region of Chile. PLoS ONE. 2018
- Single and repeated administration of methylphenidate modulates synaptic plasticity in opposite directions via insertion of AMPA receptors in rat hippocampal neurons. Frontiers in Pharmacology. 2018
- Cognitive impairment in agricultural workers and nearby residents exposed to pesticides in the Coquimbo Region of Chile. Neurotoxicology and Teratology. 2017
- In vivo sub-chronic treatment with dichlorvos in young rats promotes synaptic plasticity and learning by a mechanism that involves Acylpeptide Hydrolase instead of acetylcholinesterase inhibition. Correlation with endogenous β-amyloid levels. Frontiers in Pharmacology. 2017
- Assessing biomarkers and neuropsychological outcomes in rural populations exposed to organophosphate pesticides in Chile - Study design and protocol Environmental and occupational health. BMC Public Health. 2015
- Determination of the genotype and phenotype of serum paraoxonase 1 (PON1) status in a group of agricultural and nonagricultural workers in the Coquimbo Region, Chile. Journal of Toxicology and Environmental Health - Part A: Current Issues. 2015
- Dose-dependent regional brain acetylcholinesterase and acylpeptide hydrolase inhibition without cell death after chlorpyrifos administration. Journal of Toxicological Sciences. 2013
- Impaired learning resulting from Respiratory Syncytial Virus infection. Proceedings of the National Academy of Sciences of the United States of America. 2013
- Long-term fluoxetine treatment induces input-specific LTP and LTD impairment and structural plasticity in the CA1 hippocampal subfield. Frontiers in Cellular Neuroscience. 2013
- Neurological and neuropsychological deterioration in artisanal gold miners from the town of Andacollo, Chile. Toxicological and Environmental Chemistry. 2013
- Acutely applied MDMA enhances long-term potentiation in rat hippocampus involving D1/D5 and 5-HT2 receptors through a polysynaptic mechanism. European Neuropsychopharmacology. 2012
- Synaptic localization of acylpeptide hydrolase in adult rat telencephalon. Neuroscience Letters. 2012
- Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons. Journal of neurochemistry. 2011
- MDMA ("ecstasy") impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats. Neuroscience Letters. 2010
- Effect of short-term exposure to dichlorvos on synaptic plasticity of rat hippocampal slices: Involvement of acylpeptide hydrolase and α7 nicotinic receptors. Toxicology and Applied Pharmacology. 2009
- Erratum: Maternal Hypothyroxinemia Impairs Spatial Learning and Synaptic Nature and Function in the Offspring (Endocrinology (2008) 149 (5097-5106)). Endocrinology. 2009
- Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring. Endocrinology. 2008
- Noncholinesterase effects induced by organophosphate pesticides and their relationship to cognitive processes: Implication for the action of acylpeptide hydrolase. Journal of Toxicology and Environmental Health - Part B: Critical Reviews. 2007
- Protein kinase CK2 in postsynaptic densities: Phosphorylation of PSD-95/SAP90 and NMDA receptor regulation. Biochemical and Biophysical Research Communications. 2004
- S-methylcysteine may be a causal factor in monohalomethane neurotoxicity. NeuroToxicology. 2004
- Critical period of cortical plasticity,Periodos críticos de plasticidad cortical. Revista de Neurologia. 2003
- Heterogeneous nuclear ribonucleoprotein A2 interacts with protein kinase CK2. Biochemical and Biophysical Research Communications. 1999
- Tumour suppressor protein p53 released by nuclease digestion increases at the onset of rat liver regeneration. Journal of Hepatology. 1999
- Intracellular pH regulation in rat round spermatids. Biology of the Cell. 1997
- Changes in the activity of nuclear protein kinase CK2 during rat liver regeneration. Biochemical and Biophysical Research Communications. 1996
- Effects of benzodiazepine receptor ligands on isolated rat superior cervical ganglia neurons. Pharmacology. 1996
- Potentiation of the glycine-activated Cl- current by ethanol in cultured mouse spinal neurons. Journal of Pharmacology and Experimental Therapeutics. 1996
- Differential effects of GABAergic ligands in mouse and rat hippocampal neurons. Brain Research. 1994
- Ethanol modulation of the γ-aminobutyric acid(A)- and glycine-activated Cl- current in cultured mouse neurons. Journal of Pharmacology and Experimental Therapeutics. 1994
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capítulo
- Epidemiological Studies of Anticholinesterase Pesticide Poisoning in Chile. Anticholinesterase Pesticides. Metabolism, Neurotoxicity and Epidemiology. 2011
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documento